Archive for the ‘Genetic Edge’ Category
The Genetic Strand: Exploring a Family History Through DNA
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The Genetic Strand: Exploring a Family History Through DNA
The Genetic Strand: Exploring a Family History Through DNA The Genetic Strand is the story of a writer’s investigation, using DNA science, into the tale of his family’s origins. National Book Award winner Edward Ball has turned his probing gaze on the microcosm of the human genome, and not just any human genome — that of his slave-holding ancestors. What is the legacy of such a family history, and can DNA say something about it?
In 2000, after a decade in New York City, Ball bought a house in Charleston, South Carolina, home to his father’s family for generations, and furnished it with heirloom pieces from his relatives. In one old desk he was startled to discover a secret drawer, sealed perhaps since the Civil War, in which someone had hidden a trove of family hair, with each lock of hair labeled and dated. The strange find propelled him to investigate: what might DNA science reveal about the people — Ball’s family members, long dead — to whom the hair had belonged? Did the hair come from white relatives, as family tradition insisted? How can genetic tests explain personal identity?
Part crime-scene investigation, part genealogical romp, The Genetic Strand is a personal odyssey into DNA and family history. The story takes the reader into forensics labs where technicians screen remains, using genetics breakthroughs like DNA fingerprinting, and into rooms where fathers nervously await paternity test results. It also summons the writer¹s entertaining and idiosyncratic family, such as Ball¹s antebellum predecessor, Aunt Betsy, who published nutty books on good Southern society; Kate Fuller, the enigmatic ancestor who may have introduced African genes into the Ball family pool; and the author¹s first cousin Catherine, very much alive, who donates a cheek swab from a mouth more attuned to sweet iced tea than DNA sampling.
Writing gracefully but pacing his story like an old-fashioned whodunit, Edward Ball tracks genes shared across generations, adding suspense and personal meaning to what the scientists and Nobel laureates tell us. A beguiling DNA tale, The Genetic Strand reaches toward a new form of writing‹the genetic memoir.
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- Slaves in the Family
- The Sweet Hell Inside: The Rise of an Elite Black Family in the Segregated South (National Book Award Winner)
- Peninsula of Lies: A True Story of Mysterious Birth and Taboo Love
- Deep Ancestry: Inside The Genographic Project
- Trace Your Roots with DNA: Use Your DNA to Complete Your Family Tree
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Science on the Edge – Gene Therapy
Science on the Edge – Gene Therapy
Science on the Edge – Gene Therapy Discusses the history of genetic research that led to development of gene therapy and possibilities for future uses.
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Gene Family Targeted Molecular Design
Gene Family Targeted Molecular Design
Gene Family Targeted Molecular Design As research progresses and information continues to proliferate in the field of molecular design for therapeutic use, there is a need for a reference that brings current theory and proven practice together in a how-to volume. This reference guides scientists new to the field on how to design small molecules that interact with critical protein targets. The chapters condense useful material into a manageable format which is carefully organized and presented. It offers an essential resource for a variety of chemists in academia, and the biotech and pharmaceutical industries, as well as professionals in complementary fields.
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Science on the Edge – Genetically Engineered Food
Science on the Edge – Genetically Engineered Food : For centuries, people have improved crops by selective breeding. Today, crop scientists can develop new crops in an entirely different way: by inserting the genes that they want. While genetically engineered crops have many benefits, such as better disease resistance, there may be risks as well. (20040401)
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Leading-Edge Research in Alzheimer’s Disease
Leading-Edge Research in Alzheimer’s Disease : Dementia is a brain disorder that seriously affects a person’s ability to carry out daily activities. The most common form of dementia among older people is Alzheimer’s disease (AD), which involves the parts of the brain that control thought, memory, and language. Age is the most important known risk factor for AD. The number of people with the disease doubles every 5 years beyond age 65. AD is a slow disease, starting with mild memory problems and ending with severe brain damage. The course the disease takes and how fast changes occur vary from person to person. On an average, AD patients live from 8 to 10 years after they are diagnosed, though the disease can last for as many as 20 years. Current research is aimed at understanding why AD occurs and who is at greatest risk of developing it, improving the accuracy of diagnosis and the ability to identify those at risk, discovering, developing, and testing new treatments, and discovering treatments for behavioral problems in patients with AD. This book presents important research in the field from around the world.
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The Edge of Evolution: The Search for the Limits of Darwinism
The Edge of Evolution: The Search for the Limits of Darwinism : When Michael J. Behe’s first book, Darwin’s Black Box, was published in 1996, it launched the intelligent design movement. Critics howled, yet hundreds of thousands of readers — and a growing number of scientists — were intrigued by Behe’s claim that Darwinism could not explain the complex machinery of the cell.
Now, in his long-awaited follow-up, Behe presents far more than a challenge to Darwinism: He presents the evidence of the genetics revolution — the first direct evidence of nature’s mutational pathways — to radically redefine the debate about Darwinism.
How much of life does Darwin’s theory explain? Most scientists believe it accounts for everything from the machinery of the cell to the history of life on earth. Darwin’s ideas have been applied to law, culture, and politics.
But Darwin’s theory has been proven only in one sense: There is little question that all species on earth descended from a common ancestor. Overwhelming anatomical, genetic, and fossil evidence exists for that claim. But the crucial question remains: How did it happen? Darwin’s proposed mechanism — random mutation and natural selection — has been accepted largely as a matter of faith and deduction or, at best, circumstantial evidence. Only now, thanks to genetics, does science allow us to seek direct evidence. The genomes of many organisms have been sequenced, and the machinery of the cell has been analyzed in great detail. The evolutionary responses of microorganisms to antibiotics and humans to parasitic infections have been traced over tens of thousands of generations.
As a result, for the first time in history Darwin’s theory can be rigorously evaluated. The results are shocking. Although it can explain marginal changes in evolutionary history, random mutation and natural selection explain very little of the basic machinery of life. The “edge” of evolution, a line that defines the border between random and nonrandom mutation, lies very far from where Darwin pointed. Behe argues convincingly that most of the mutations that have defined the history of life on earth have been nonrandom.
Although it will be controversial and stunning, this finding actually fits a general pattern discovered by other branches of science in recent decades: The universe as a whole was fine-tuned for life. From physics to cosmology to chemistry to biology, life on earth stands revealed as depending upon an endless series of unlikely events. The clear conclusion: The universe was designed for life.
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